Senator Dale Bumpers

Introduction Dale Bumpers was born in 1925 and brought up in Charleston, Arkansas. When he was a young boy, the U.S. underwent through the Great Depression forcing Bumpers to do odd jobs to support his family. Bumpers spent the better part of the Great depression working in farms, canneries, and even acted as the hearse driver in his father’s funeral.Advertising We will write a custom essay sample on Senator Dale Bumpers specifically for you for only $16.05 $11/page Learn More During that period, he also worked as an attendant in a small grocery store. Before passing away, the senior Bumpers had served a one term as a state legislator. From a young age, the senior Bumpers taught his son that being elected in to a political office was the biggest achievement that a man could have. This must have been the young man’s motivation for his political career later on in life. (Worrell 1) As a young boy, Dale Bumpers spent his life within Arkansas. He attended public schools within his hometown and even went to the University of Arkansas where he got his undergraduate. Finally, he attended the Northwestern University Law School in Chicago where he attained his graduate degree in law. Before joining the University for his Graduate Degree in law, Bumpers first had a brief stint in the U.S. military. During World War II, that lasted from 1943-1946, he served in the American Marine Corps. During his university days, Bumpers became a great admirer of Democratic politics especially those of its presidential candidate Aldai Ewing Stevenson. Bumpers completed his law degree in 1952 and was admitted into the Arkansas bar the same year. In the same year, he became the Charleston city attorney a position he held until 1970. His experience as the Charleston attorney inspired him to write an autobiography The Best Lawyer in a One-Lawyer Town: A Memoir that was published in 2003. (Bumpers 8) Although Bumpers had long been interested in poli tics, he had not made his political ambitions explicit. However, this changed in 1970 when he suddenly announced his interest for the governorship seat on a Democratic part ticket. However, some thought this to be impossible as he had to battle for the nomination with other established candidates led by a former Governor Orval Faubus and Joe Purcell who was the then Attorney General among others. Although he was a newcomer with no big name to his cap, he won the people’s heart with his rich spoken language and personal charisma. During the first round of the elections, Bumper managed to go into the runoff stage with a previous governor Orval Faubus.Advertising Looking for essay on government? Let's see if we can help you! Get your first paper with 15% OFF Learn More Although Bumpers had a slim victory that led him to the runoff, he got a landslide victory during the next phase of the elections. When the general election finally came, Bumpers emerged victorious o ver Winthrop Rockefeller the then serving Republican Governor. His election as the governor marked his long political career in the United States. He was reelected as the governor in 1972 again defeating a serious pool of both Democratic and Republican contenders. (Biographical Directory of the United States Congress) The political career of Dale Bumpers continued to shine brighter and brighter leading into his election into the United States Senate in 1974. This was a position that Bumpers would hold for four consecutive terms until his retirement in 1998. In 1974, he won against John Harris Jones and in 1980 he defeated William Clark who was a Democratic turned Republican. In the 1986 elections Bumpers was able to retain his seat by defeating Asa Hutchinson a trend that he maintained in 1992 when he trounced future Governor Mike Huckabee. In 1998, he was ineligible for reelection having served the maximum four terms and he retired gracefully from elective office. (Blair 72) As a f ederal government official, Bumpers chaired many committees, which were mandated with bettering the welfare of the American people. This included chairing the Senate Committee on Small Business and Entrepreneurship, which was mandated with raising the standards of small business people in America. Before his retirement, he also served as a junior member of a committee tasked with looking into Energy and Natural Resources affairs. After his retirement, Bumpers helped his long time friend and the then President Bill Clinton escape an impeachment trial against him. (The Pbs NewsHour) Even after retirement, Bumpers and his wife continued to support their noble cause of childhood vaccination. This led to the establishment of the Dale and Betty Bumpers Vaccine Research Center that seeks to further research in vaccine growth. Today, Dale Bumpers is regarded as one of the greatest American senators who are still alive. Conclusion Dale Bumpers endured a challenging childhood to become one of the greatest politicians that America has ever produced. During his childhood, Bumpers had to perform odd chores in order to pay his bills. However, he beat all the odds to become an attorney and later a Governor. He was later elected in the Senate for four consecutive terms until his retirement in 1998. During his tenure as a senator, Bumpers served in many key committees including the Senate Committee on Small Business and Entrepreneurship and the Energy and Natural Resources Committee. After his retirement, his defense helped President Clinton to overcome an impeachment trial against him.Advertising We will write a custom essay sample on Senator Dale Bumpers specifically for you for only $16.05 $11/page Learn More Works Cited Biographical Directory of the United States Congress. Bumpers, Dale, (1925- ), n.d. Web. Oct 25. 2010. http://bioguide.congress.gov/scripts/biodisplay.pl?index=b001057. Blair, Diane. The Big Three of Late Twentieth-Century Arka nsas Politics: Dale Bumpers, Bill Clinton and David Pryor. The Arkansas Historical Quarterly, 1995. 53-79. Print. Bumpers, Dale. The Best Lawyer in a One-Lawyer Town: A Memoir. New York: Random House, 2003. 1-12. Print. The Pbs NewsHour. The Impeachment Trial. Former Senator Dale Bumpers, 1999. Web. Worrell, Diane. The Arkansian. Senator Dale Bumpers Project Begins, 2010. 1-36. Print. This essay on Senator Dale Bumpers was written and submitted by user C0ry to help you with your own studies. You are free to use it for research and reference purposes in order to write your own paper; however, you must cite it accordingly. You can donate your paper here.

Why Laboratory-Grown Meat Is Not Vegan

Why Laboratory-Grown Meat Is Not Vegan On August 5, 2013, Dutch scientist Mark Post presented the worlds first laboratory-grown burger at a press conference, where he shared the patty with two food critics. Although the foodies found the flavor lacking, Post stated that the purpose of the exercise was to show that it could be done; flavor could be improved later. Laboratory-grown meat may seem at once a Frankenfoods nightmare, as well as a solution to the animal rights and environmental concerns regarding meat-eating. While some animal protection organizations applaud the idea, meat grown in a laboratory could never be called vegan, would still be environmentally wasteful, and would not be cruelty-free. Laboratory-Grown Meat Contains Animal Products Although the number of animals affected would be greatly reduced, laboratory-grown meat would still require the use of animals. When scientists created the first laboratory-grown meat, they started with muscle cells from a live pig. However, cell cultures and tissue cultures typically do not live and reproduce forever. To mass-produce laboratory-grown meat on an ongoing basis, scientists would need a constant supply of live pigs, cows, chickens and other animals from which to take cells. According to The Telegraph, Prof Post said the most efficient way of taking the process forward would still involve slaughter. He said: Eventually my vision is that you have a limited herd of donor animals in the world that you keep in stock and that you get your cells from there. Furthermore, these early experiments involved growing the cells â€Å"in a broth of other animal products,† which means that animals were used and perhaps killed in order to create the broth. This broth is either the food for the tissue culture, the matrix upon which the cells were grown, or both. Although the types of animal products used were not specified, the product could not be called vegan if the tissue culture was grown in animal products. Later, The Telegraph reported that pig stem cells were grown using a serum taken from a horse fetus, although it is unclear whether this serum is the same as the broth of animal products used in the earlier experiments. Posts final experiments involved shoulder muscle cells taken from two organically raised calves and grown in a broth containing vital nutrients and serum from a cow fetus. Its Still Considered Wasteful Scientists are hopeful that laboratory-grown meat will reduce greenhouse gas emissions, but growing animal cells in a laboratory would still be a waste of resources, even if the cells were grown in a vegan medium. Traditional animal agriculture is wasteful because feeding grain to animals so that we can eat the animals is an inefficient use of resources. It takes 10 to 16 pounds of grain to produce one pound of feedlot beef. Similarly, feeding plant foods to a muscle tissue culture would be wasteful compared to feeding plant foods to people directly. Energy would also be required to â€Å"exercise† the muscle tissue, to create a texture similar to meat. Growing meat in a laboratory may be more efficient than feedlot beef because only the desired tissues would be fed and produced, but it cannot be more efficient than feeding plant foods directly to people. However, Pamela Martin, an associate professor of geophysical sciences at the University of Chicago, co-authored a paper on the increased greenhouse gas emissions of a meat-based diet over a plant-based diet, and questions whether laboratory-grown meat would be more efficient than traditional meat. Martin stated, â€Å"It sounds like an energy-intensive process to me.† As reported in the New York Times, Post replied to a question about whether vegetarians would like lab-grown meat, Vegetarians should remain vegetarian. That’s even better for the environment. Perpetuating Animal Use and Suffering Assuming that immortal cell lines from cows, pigs and chickens could be developed and no new animals would have to be killed to produce certain types of meat, the use of animals to develop new types of meat would still continue. Even today, with thousands of years of traditional animal agriculture behind us, scientists still try to breed new varieties of animals who grow larger and faster, whose flesh has certain health benefits, or who have certain disease resistance. In the future, if laboratory-grown meat becomes a commercially viable product, scientists will continue to breed new varieties of animals. They will continue to experiment with cells from different types and species of animals, and those animals will be bred, kept, confined, used and killed in the never-ending search for a better product. Also, because current research into laboratory-grown meat is using animals, it cannot be called cruelty-free  and purchasing the product would support animal suffering. While laboratory-grown meat would probably reduce animal suffering, it’s important to keep in mind that it is not vegan, it is not cruelty-free, its still wasteful, and animals will suffer for laboratory-grown meat.

Analysis of Linear DNA Genomes Separation in Gel Electrophoresis

Agarose gel electrophoresis has been widely used as a form of separating DNA genomes in varying sizes from 100 kp upto 25 kb. Isolation of Agarose gel is obtained from the genera Gelidium and Gracilaria.in the gelato process, the polymers of agarose often form an association of none covalent which form networks of pore sizes which determine the molecular ability of sieving properties. Use of gel electrophoresis is beneficial in separation of DNA genomes. Electrophoresis process is key in separating the different nucleic acids using various sizes and charges depending on the contents of the solution. In this experiment, lab analysis of gel was used to put gel solutions in charged nucleic acids for separation purposes. At this point the larger DNA and RNA have a hard time in separating thus allowing time for separation of the genomes based on the sizes. The rate of separation of the DNA molecule in the experiment was determined by the rate at which the sizes of the DNA, the concentration of the gel, DNA Conformation present, voltage degree applied, ehidium bromide solution introduced, type of agarose and the buffer being utilized in electrophoresis. After the process of separation, DNA molecules will be able to be visualized in the UV light using staining process to identify the different genomes. Thus in essence DAN electrophoresis defines the process by which the DNA migrates in the supporting medium. Most of electrophoresis is carried in agarose gels in narrow polymers of gels using pores of different sizes, this sieving provides a means by which the pores gives an opportunity for the DNA molecules to go through the pores at different sizes thus being separated using molecular weights. Thus this laboratory report uses agarose Gels while staining with ethidium bromide   to assess the separation process of the different DNA genomes. Thus it seeks to investigate the DNA genome separation to assess the different nucleic acids by their respective sizes. Refer to the Lab Manual 5 for in-depth methodology and procedure. Diagrammatic presentation of gel DNA Table 1; Showing gel electrophoresis picture Table 2; Showing curve presentation of the base pairs against distance travelled Table 3; Showing table figure for the curve Table 4; Showing how to calculate base pairs Example suppose we have a base pair having travelled 0.3 cm, then draw a line as illustrated above and take the readings on the corresponding logbp and take the anti log, which you get the base pair size. Table 5; Showing the sizes of pUC19 and their insert sizes Agarose gel electrophoresis has been utilised as a common method for separation of proteins, (Kryndushkin et al., 2003). The basic forms of nucleic acids can be separated through the aid of electrification process whereby charged molecules move to the anode side. This migration as depicted in the experiment ensures that molecules which have lower molecular weight are able to move faster, (Sambrook & Russel 2001). The process of electrophoresis is a crucial step in ensuring purification process of the desired DNA bands. In this experiment the usage of ethidium bromide is essential in visualizing the staining of the transcend DNA molecules. In this task, the Agarose gel electrophoresis plays a key role in ensuring the characteristics of DNA are obtained without any alterations. This experiment has yielded results which have enabled determination of DNA fragments sizes through digestion by restriction enzymes. The visualization has been effected with the use of ethidium bromide which is a common agent in nucleic acid purification process. The Agarose gel concentration on this task entailed the separation of the gel using agarose gel concentration of 0.2%w/v having bands from 0.1-1 kb. The distance travelled by DNA molecules in electrophoresis is directly proportional to the size of the DNA itself. The agarose gel is beneficial in ensuring that there are movements based on their sizes. With the various differences between the various rates of the DNA molecules in the gel solution, they are separated based on the size of the bases. The relationship built between the varied sizes of the DNA genome. The sieving of DNA is done through the size which it bears, (Southern, 1975). The length of DNA strands often vary from 50 base pairs to upto million s base pairs which agarose gel electrophoresis can be effective in separating them , the migration and distance travelled is linked on the concentration of the agarose used to prepare the gel. Concentrations having lower concentration are able to travel faster in the distance travelled and vice versa. In this study agarose gel of 2% has been used which was effective in separating the DNA at range of 0.1-1 kb, the low percentile gels often signify gels which are weak. Double stranded DNA moves faster as the molecules travels; its speed is inversely proportional to the logarithm of base pairs. This linked and established relationships depends on the strength of the of gel composition. The distance travelled by the digested genome signifies that there is action of restriction enzymes which shows that there restrictions which have taken place, thus distinguishing the variability linked to genetics and enzyme cost. The digested fragments were this separated using the agarose gel electrophoresis which showed continuous smear on the gel surface with the distribution of the difference fragment sizes being established. Digested pUC19 is a plasmid and able to transform itself on the transformation process where it can be able to multiply itself and express. Undigested pUC19 originate from E coli and contain high number of base pairs. The transformation efficiently portrayed shows that smaller pUC19 plasmid sin E choli can be manipulated and be transformed from the ampicilin forms. This shows that the DNA is in contact form with plasmid DNA being intact and with presence of viral chromosomes which can be transformed into high efficiencies. This transformation is through the resulting effect of digestion of peri plasmids. The undigested Puc19 shows presence base pairs which have the ability to perform recombination and be incorporated into cells, (Goto, Kenta & Yukio, 2013). The lanes which have recombination factor is able to facilitate the cloning of DNA in host cells.   This signifies recombination of various fragments of gel solution. The lanes that have been generated originated from digestion of particular DNA, which gives it equimolar amounts. Based on the lanes, there is variation on the number of non molar amounts, thus signifying that there is difference in band lengths. Others have shown to represent circular forms of the plasmids which is dependent on the age and quality of the plasmids. The existence of three forms of DNA formation which exists include linear formation, open circular formation and supercoiled forms. Plasmid DNA have been prevalently been studied in laboratory studies. After its preparation they exists in the three forms above. With good plasmid preparation, DNA often form plasmid which exist in any one strands of the DNA, this break causes the release of the phosphordiester backbones of the DNA to be released out. The visualising process of the agarose gel using the standard control tool is key to assess whether the bands have created a generation or not. Closer bands are well compressed than far away bands as indicated in the gel view. The standard marker used in this experiment was essential in ensuring that the standards sizes are generated using base pairs. This result signifies that electrophoresis is an effective way of separating nucleic acids. High gel agarose gives room for handling of low percentage gel separation. Due to the size of the base pair present in this experiment, has utilised field gel electrophoresis. This is   comparable to studies done (Lee et al, 2012), which have shown that sizes of DNA can be separated effectively through plotting on the log of molecular weight and different bands of DNA against the distance moved, this portray how different forms of gel can be able to move at different speeds. Super coiled plasmid DNA have sown to move faster, while those in linear formation travel averagely while open circular travel slowly. Goto, K., & Nagano, Y. (2013). Ultra-low background DNA cloning system. PloS one, 8(2), e56530. Kryndushkin DS, Alexandrov IM, Ter-Avanesyan MD & Kushnirov VV (2003). Yeast [PSI+]   prion aggregates are formed by small Sup35 polymers fragmented by Hsp10. Journal of Biological Chemistry.278 (49): 49636. Lee, P. Y., Costumbrado, J., Hsu, C. Y., & Kim, Y. H. (2012). Agarose gel electrophoresis for the separation of DNA fragments. Journal of visualized experiments: JoVE, (62). Sambrook J&Russel DW(2001). Molecular Cloning: A Laboratory Manual 3rd Ed. Cold Spring Harbor Laboratory Press. Cold Spring Harbor, NY. Southern, E. M. (1975). Detection of specific sequences among DNA fragments separated by gel electrophoresis. J mol biol, 98(3), 503-517.

The journey of Irish immigrants surviving Research Paper

The journey of Irish immigrants surviving - Research Paper Example It will not be incorrect to state that millions of people were migrated to America in different cities but majority came and settled in New York because it was the largest city in America. In addition, immigrants came with a hope that they will live in a free country and they had this hope that they will live in their dream America. The reason was that America was economically stable at that time and there were various opportunities to earn money. However, the local people didn’t want to work immigrants in their country and live a better life than them. It was because the local Americans were not able to accept the fact people from other country can lead them and can be better than them. The Americans disregarded Irish people and treated them as poor people2. Irish immigrants wanted to achieve the dream American life like other Americans were having in their homeland. It was the reason due to which they were working hard to get the desired life. Though, it was difficult for them but they were trying hard by focusing on the education and seeking jobs for them. However, they were unable to get their desired life because they were not accepted by the local Americans3. Thoughts above occurred me when I stepped into the Lower East Side Tenement Museum. It looks like a normal old building from the outside. I stood at the outside for a while when the guide described the museum for me. All the Irish immigrants lived in the building and the costumers of the bar on the first floor shared only three toilets. People lived here before had to carried whole baskets of water themselves from the first floor to fifth floor. The basket now was filled with the same amount of weight of stones instead to let me try how heavy the basket was before. It was really heavy, and I knew that I couldn’t even make it to the second floor. Then I got into the room, and almost

Changes in technology anticipated to change the pattern of pollutant Research Paper - 1

Changes in technology anticipated to change the pattern of pollutant emissions - Research Paper Example Man cannot altogether stop using fossil fuels but moves to decrease energy consumption by developing new technologies designed for energy efficiency is the best way to alleviate the state of the environment. New Technologies refer to both innovations in production or generation of energy and its actual use. Generation of energy from solar, wind, geothermal, tides and hydroelectric are, currently, being implemented and studied. The graph below shows that new technologies in the generation of energy from renewable resources delivers needed energy but emits less CO2 emissions. US-NASA predicts further decrease in CO2 emissions in the future. New technologies developed for actual use or consumption of energy seeks to maximize these renewable sources of energy in the three major areas of transportation; industrial energy usage; and, in commercial and residential buildings. This is clearly exemplified in the Modern Refrigerators and the introduction of Electronic Vehicles. The diagram below shows that the energy use per refrigerator decreased by two-thirds since the introduction of new energy efficient refrigerators. The continued study and development of refrigerator efficiency improvements has proven to be a success. The introduction of Electronic Vehicles according to the research by Micheal Wang, Mark DeLuchi and Daniel Sperling has the effects of lowering the emissions of HC, CO, NO, SO, and particulates. With continued use, they predict a significant reduction in California that will help major air basins in California meet national ambient air quality standards. It cannot be denied that new technologies decrease pollutant emissions. To be fully effective, according to study conducted by Amit Garg, P.R. Shukla, Debyani Ghosh, Manmohan Kapshe and Nair Rajesh, laws and governments must give full support to the endeavor. Garg A., Shukla P., Ghosh D., Kapshe M., & Rajesh N. Future Greenhouse Gas and Local Pollutant Emissions for India: Policy

The Fate Of Drugs And Drug Development Essay Example for Free

The Fate Of Drugs And Drug Development Essay The most appropriate dosage form for administering drugs to pediatric patients is the low-dose liquid format, computed through the patient’s kilogram body weight.   Pediatric patients are generally small in body size and thus a very low dose is sufficient in attaining the desired clinical outcome.   For adults, the maximum dose in tablet or capsule form can be administered. (2)   A drug in tablet or capsule form easily disintegrates in the stomach and the contents are further dissolved as it passes through into the small intestines, where absorption takes place. (3)   Pharmacokinetics pertains to the action of drugs in terms of absorption, as well as metabolism within the human body (Sharan et al., 2009).   This field also deals with the distribution of the drug and its eventual excretion. (4)   Pharmacokinetics involves a specific order of activities with regards to a drug because it describes the actual steps that occur during drug intake.   Before the actual effect of a drug takes place, the active ingredient needs to be absorbed through the intestinal lining and further distributed to the target areas of the body.   Metabolism then occurs which is the incorporation of the drug to the target areas.   Any excess or used drugs are then removed from the body through the process of excretion. (5)   The chemical nature of the drug determines the absorption ability of a drug.   Lipophilic drugs generally enter the cells quickly, due to its similarity in composition to the plasma membrane.   High dosages can also increase the absorption of a drug into cells. (6)   Pharmacodynamics pertains to the effect of a drug in terms of its biochemistry and physiological action in the human body. (7)   One main action of a drug is to stimulate the human body to perform a specific action (Kang and Lee, 2009).   Another type of drugs is the depressant, which slows down specific activities in the body.   There are also cytotoxic drugs that kill specific cells in the body.   Other drugs are aimed to replace certain substances that are lacking or at very low levels in the body. (8)   The general relationship observed is that when a drug response is attained, the serum concentration of that same drug is found to be at its highest dose.   Drug manufacturing is mainly based on the preparation of capsules or tablets that contain the minimum amount of the drug that can exert a response in the human body (Najib, 2009). (9)  Ã‚   An adverse effect of a drug occurs when there are more than enough amounts that are circulating in the body of a patient.   The excess amount can cause damage to the liver of an individual (Marin et al., 2009).   Drug-drug interactions pertain to the effect of one drug on another, if they are administered at the same time.   The presence of another drug may either interfere or enhance the effect of another drug and thus it is important for a physician to know all the drugs that a patient takes before prescribing or administering any new drugs. References Kang, J.S. and Lee, M.H.   (2009).   Overview of therapeutic drug monitoring.   Korean Journal of Internal Medicine, 24, 1-10. Marin, J.J., Briz, O., Perez, M.J., Romero, M.R. and Monte, M.J.   (2009).   Hepatobiliary transporters in the pharmacology and toxicology of anticancer drugs.   Frontiers in Bioscience, 14, 4257-4280. Najib, J.   (2009).   The efficacy and safety profile of lisdexamfetamine dimesylate, a prodrug of d-amphetamine, for the treatment of attention-deficit/hyperactivity disorder in children and adults.   Clinical Therapeutics, 31, 142-176. Sharan, K., Siddiqui, J.A., Swarnkar, G., Maurya, R. and Chattopadhyay, N.   (2009).   Role of phytochemicals in the prevention of menopausal bone loss: Evidence from in vitro and in vivo, human interventional and pharma-cokinetic studies.   Current Topics in Medical Chemistry, 16, 1138-1157.

The Ecstasy Debate: Weighing The Good And The Bad :: Biology Essays Research Papers

The Ecstasy Debate: Weighing The Good And The Bad Ever since its first synthesis 80 years ago, the seemingly harmless nature of the drug ecstasy has been the subject of much debate. While many scientists are convinced that there is a darker side to the euphoria-inducing pill than meets the eye, the millions of users insist that no such danger exists. In fact, while I conducted my research on the subject, I discovered that to some extent, the users' concept is true - ecstasy does seem to be far less harmful than any of the other popularized drugs of the century. But why, then, in 1985 was this limitlessly pleasurable drug outlawed (1), with such a weak case against it? Is the scientific world's overly cautious attitude preventing us from experiencing a limitless pleasure unlike anything we have ever known? These were the questions I sought to have answered. 3,4 - Methylenedioxymethamphetamine, or MDMA as it has come to be called, is a psychoactive drug with a chemical structure similar to the stimulant methamphetamine and the hallucinogen mescaline, and demonstrates both psychedelic and stimulant effects (3). It was first synthesized by a German company in 1912 to be used to help develop more advanced therapeutic drugs (1). In the 1970s, MDMA was used to facilitate psychotherapy by a group of therapists in the United States (5). Not until the 1980s and early 1990s did the drug gain worldwide popularity as the illicit "ecstasy" (5), the drug that would eventually stir a wave of excitement among young people everywhere. Ecstasy use, which saw its roots in the hippie generation of the 1970s, has since grown exponentially. Ecstasy tablets confiscated by the Drug Enforcement Administration increased from 13,342 in 1996 to 950,000 in 2000 (4). According to a study conducted by the University of Michigan's Institute for Social Research in 1998, 4.3 percent of 8th graders, 7.3 percent of 10th graders, and 11 percent of 12th graders reported they had used MDMA at some point (4). However, by far the age group with the heaviest use (1.4 million Americans) of the drug was reported for those between 18 and 25 years of age (4). So much ecstasy is entering our country at present that the Customs Service has developed an ecstasy command center and is training dogs to sniff out the drug (2). What is it that lures so many people to "experiment" with ecstasy and tantalizes them to want more?